Diastolic dysfunction in elderly patients referred to the heart failure diagnostic clinic

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[Diastolic dysfunction and diastolic heart failure].

There are frequent clinical Cases in Cardiological practice when cardiac failure develops together with normal systolic function of left ventricle. In these patients after revealing the diastolic dysfunction the heart diastolic failure is diagnosed, but in frequent cases this diagnosis is based on exclusion method. According to Framingham data the number of patients with clinically manifested d...

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Mechanisms of diastolic dysfunction in heart failure.

Abnormalities of diastole are common to most forms of congestive heart failure (HF). Diastolic function is broadly defined as the ability of the heart to fill adequately and at normal pressure to charge the ventricular pump for each subsequent contraction. It is determined by both active and passive processes occurring at the level of the myocyte, extracellular matrix, and left ventricular cham...

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Diastolic dysfunction and diastolic heart failure: diagnostic, prognostic and therapeutic aspects

Left ventricular (LV) diastolic dysfunction (DD) and diastolic heart failure (HF), that is symptomatic DD, are due to alterations of myocardial diastolic properties. These alterations involve relaxation and/or filling and/or distensibility. Arterial hypertension associated to LV concentric remodelling is the main determinant of DD but several other cardiac diseases, including myocardial ischemi...

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Differentiating diastolic dysfunction from classic heart failure

Heart failure (HF) is characterized by an impaired ability of the ventricle to fill with and eject blood commensurate with the metabolic demands and requirements of the body, and has emerged as a major cause of morbidity and mortality in the developed world. Approximately 50% of HF patients have preserved ejection fraction, and lack overt signs of systolic failure, but rather have deficits in v...

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Diastolic heart failure, diastolic left ventricular dysfunction and exercise intolerance.

The phenomenon of “diastolic heart failure” is rightly receiving greater attention (1–4); community-based studies such as those in Framingham (5) and Olmsted County (6) show that up to 50% of older persons with heart failure do not have impaired left ventricular (LV) systolic function to account for this, and that the condition is usually associated with LV hypertrophy and is preceded by elevat...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2003

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(03)81956-3